Onco Wiki / Maladie

Carcinome colorectal (CRC)

Vue déterministe de l'entité source de la LJAM. L'autorité clinique demeure avec les ID de la source cités et l'état d'approbation de l ́examinateur.

IDDIS-CRC
TypeMaladie
Alias
Cancer de l'intestinCancer du colon + Cancer rectalCarcinome colorectalКолоректальний рак
Étatreviewed 2026-04-26 | pending_clinical_signoff
MaladiesAucune déclaration
SourcesSRC-ESMO-COLON-2024 SRC-NCCN-COLON-2025

Informational support. All recommendations must be verified by a qualified oncologist. Engineering checks are not clinical validation or treatment approval.

Source YAML

icd_o_3_morphology8140/3
icd_o_3_topography["C18", "C19", "C20"]
icd_10C18-C20
who_classificationWHO Digestive System Tumours 5th ed (2019): Adenocarcinoma of the colon and rectum

Capacités

Notes

Combined colon + rectum scope. The two share most systemic-therapy decisions (FOLFOX/CAPOX adjuvant, FOLFIRINOX/FOLFOX+bev/cetux/panit metastatic, pembro MSI-H 1L) but rectum has additional neoadjuvant CRT / TNT decisions that the current schema cannot cleanly express (see PROPOSAL §17). For now, rectum-specific neoadjuvant logic is documented in Indication.notes free-text; full sequencing awaits proposal ratification. Required biomarkers per NCCN colon v4.2025 §pretreatment for any stage III–IV: MSI / dMMR (treatment-defining for MSI-H), RAS extended (KRAS exons 2-4 + NRAS exons 2-4), BRAF V600E, HER2 (rare but actionable in RAS-WT).

Utilisé par

Pertinence thérapeutique

Algorithmes

Maladie

Chapitres du manuel

Indication

Procédures

Questionnaires

Signal d’alerte

Sources