Onco Wiki / Disease

Esophageal carcinoma (squamous + adeno)

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

IDDIS-ESOPHAGEAL
TypeDisease
Aliases
Esophageal SCC + adenocarcinomaEsophageal cancerEsophageal carcinomaКарцинома стравоходу (плоскоклітинна + аденокарцинома)
Statusreviewed 2026-04-26 | pending_clinical_signoff
DiseasesNone declared
SourcesSRC-ESMO-ESOPHAGEAL-2024 SRC-NCCN-ESOPHAGEAL-2025

Informational support. All recommendations must be verified by a qualified oncologist. Engineering checks are not clinical validation or treatment approval.

Source YAML

icd_o_3_morphology8070/3
icd_o_3_topography["C15"]
icd_10C15
who_classificationWHO Digestive System Tumours 5th ed: Esophageal squamous cell carcinoma + esophageal adenocarcinoma

Capabilities

Notes

Scaffolded for Phase GI-1: 1 RF (high-grade dysphagia / aspiration — most common acute presentation), 1 indication (CROSS-style scaffold noting RT not modellable), 1 algorithm. Full histology-stratified algorithm (squamous: definitive CRT for unresectable, CROSS for resectable; adeno: FLOT preferred for resectable, CROSS alternative) + adjuvant nivolumab post-CROSS without pCR + metastatic biomarker- stratified ICI/chemo combos await ratification + clinical authoring. Histology branching is critical — squamous and adeno have largely parallel but partially divergent paradigms. Per-prompt allowance: one disease YAML covers both, with histology field on Indication applicability.

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