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Heavy alcohol consumption — defined as >14 drinks/week (women) or >21 drinks/week (men) p...

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

IDRF-LIFESTYLE-ALCOHOL-CANCER-PREVENTION
TypeRed flag
Statusreviewed 2026-05-18 | pending_clinical_signoff
DiseasesDIS-BREAST DIS-CRC DIS-ESOPHAGEAL DIS-HCC
SourcesSRC-NCCN-BCELL-2025

Red Flag Origin

DefinitionHeavy alcohol consumption — defined as >14 drinks/week (women) or >21 drinks/week (men) per US DHHS / WHO thresholds — OR cumulative lifetime alcohol use ≥40 drink-years. IARC Group 1 carcinogen — established etiological driver of head + neck squamous cell carcinoma (oral cavity + oropharynx + larynx + hypopharynx), esophageal SCC, hepatocellular carcinoma (via cirrhosis), colorectal cancer, female breast cancer (dose- response from ≥1 drink/day), and probably pancreatic + gastric. Alcohol-tobacco interaction is multiplicative for oral-pharyngeal- laryngeal-esophageal-SCC. Cessation / moderation produces meaningful cancer-incidence reduction over decades. Prevention- persona RedFlag (§20 v0.3 lifestyle pilot).
Clinical directioninvestigate
Categoryother

Trigger Logic

{
  "any_of": [
    {
      "finding": "alcohol_heavy_use_above_threshold",
      "value": true
    },
    {
      "finding": "alcohol_lifetime_drink_years_ge_40",
      "value": true
    },
    {
      "finding": "alcohol_with_concurrent_tobacco_use",
      "value": true
    }
  ],
  "type": "lab_value"
}

Notes

Prevention-persona RedFlag for heavy alcohol use. Engine routes to PreventionPlan recommending structured cessation/moderation counseling + pharmacotherapy + appropriate cancer screening (esophageal endoscopy for high-risk, breast cancer surveillance for women). STUB pending two-Clinical-Co-Lead signoff per CHARTER §6.1 dev-mode.

Used By

Indications