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Regular consumption of very hot beverages (≥65°C / 149°F) per IARC Monograph 116 (2016) —...

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

IDRF-LIFESTYLE-HOT-BEVERAGES-PREVENTION
TypeRed flag
Statusreviewed 2026-05-18 | pending_clinical_signoff
DiseasesDIS-ESOPHAGEAL
SourcesSRC-NCCN-BCELL-2025 SRC-NCCN-ESOPHAGEAL-2025

Red Flag Origin

DefinitionRegular consumption of very hot beverages (≥65°C / 149°F) per IARC Monograph 116 (2016) — applies primarily to teas (especially traditional preparation styles in regions of Iran, Turkey, China, parts of South America with maté), but also coffee/water consumed at scalding temperatures. IARC Group 2A (probably carcinogenic) classification — associated with esophageal squamous-cell carcinoma (ESCC), particularly in regions with high background ESCC incidence. Mechanism: thermal injury to esophageal epithelium → chronic inflammation → field carcinogenesis. Note: at typical Western coffee/tea temperatures (<60°C), no association observed; coffee + tea per se are not carcinogenic. Prevention-persona RedFlag (§20 v0.3 lifestyle pilot).
Clinical directioninvestigate
Categoryother

Trigger Logic

{
  "any_of": [
    {
      "finding": "very_hot_beverage_consumption_ge_65c",
      "value": true
    },
    {
      "finding": "traditional_tea_culture_high_temperature",
      "value": true
    },
    {
      "finding": "scalding_beverage_intake_regular",
      "value": true
    }
  ],
  "type": "lab_value"
}

Notes

Prevention-persona RedFlag for very hot beverage consumption ≥65°C. IARC Group 2A classification (2016). Most relevant in regions with high background ESCC incidence (Iran, Turkey, China, parts of South America); effect size modest in low-incidence regions. Engine routes to PreventionPlan recommending beverage-temperature counseling. STUB pending two-Clinical-Co-Lead signoff per CHARTER §6.1 dev-mode.

Used By

Indications