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Carcinoma de células basais (BCC)

Visão determinística da entidade fonte YAML. A autoridade clínica permanece com os IDs de fonte citados e estado de assinatura do revisor.

IDDIS-BCC
TipoDoença
Alegais
BCCCarcinoma de células basaisCâncer de pele de células baso-celularesafecções do sistema nervosoúlcera de roedoresБазально-клітинна карцинома (БКК)
Estadoreviewed 2026-05-04 | pending_clinical_signoff
DoençasNenhuma declaração
FontesSRC-NCCN-MELANOMA-2025 SRC-NCCN-SKIN-2025

Informational support. All recommendations must be verified by a qualified oncologist. Engineering checks are not clinical validation or treatment approval.

Fonte YAML

icd_o_3_morphology8090/3
icd_o_3_topography["C44"]
icd_10C44
who_classificationWHO Classification of Skin Tumours 5th ed (2023): Basal cell carcinoma

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The vast majority of BCCs are cured with surgery or radiation. Hedgehog inhibitors (vismodegib, sonidegib) are approved only for locally advanced unresectable or metastatic BCC — a small fraction of all BCCs. Gorlin syndrome (PTCH1 germline) warrants genetic counseling and lifelong surveillance. SMO inhibitors cause significant side effects (muscle cramps, alopecia, dysgeusia, weight loss) limiting long-term use. Cemiplimab (anti-PD-1) is FDA-approved for locally advanced/metastatic BCC after HHI failure.

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