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Tumor de Wilms (nefroblastoma)

Vista determinista de la entidad fuente YAML. La autoridad clínica sigue con los ID de fuente citados y estado de firma del revisor.

IDDIS-WILMS
TipoEnfermedad
Aliaces
Wilms asociada a Beckwith-WiedemannNefroblastomaTumor de riñón pediátricoWilms asociados a la WAGRTumor de WilmsПухлина Вільмса (нефробластома)
Situaciónreviewed 2026-05-18 | pending_clinical_signoff
EnfermedadesNinguna declarada
FuentesSRC-COG SRC-NCCN-PEDIATRIC-SARCOMA

Informational support. All recommendations must be verified by a qualified oncologist. Engineering checks are not clinical validation or treatment approval.

Fuente YAML

icd_o_3_morphology8960/3
icd_o_3_topography["C64"]
icd_10C64
who_classificationWHO Urinary and Male Genital Tumours 5th ed (2022): Nephroblastoma (favorable histology + anaplastic variant)

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Notas

Two major treatment philosophies: COG (North American) — upfront surgery + adjuvant chemo (± RT) based on stage + histology. SIOP (European) — pre-operative chemo (4-6 weeks) → surgery → adjuvant based on response + histology. Both achieve >90% OS in favorable- histology disease. Chemotherapy backbone: vincristine + actinomycin ± doxorubicin per stage / histology / risk group. Anaplastic histology requires intensified regimens (ifosfamide + carboplatin + etoposide). Cascade screening obligatory for syndromic carriers — abdominal US q3-4 months from birth to age 7 in Beckwith-Wiedemann / WAGR.

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