OpenOnco · Diagnostic · Suspect endometrial · PMB + thickened endometrium 14 mm
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OpenOnco · Workup Brief · DIAGNOSTIC PHASE
Pre-tumor-board workup brief
DPLAN-PZ-DIAG-ENDO-001-V1 · v1 · 2026-05-13
Patient
PZ-DIAG-ENDO-001 · suspicion lineage: endometrial_carcinoma
Tissues: endometrium, uterus · Hypotheses: DIS-ENDOMETRIAL
64F postmenopausal × 12 years (LMP age 52) presents with new-onset postmenopausal_bleeding × 6 weeks, intermittent spotting → frank bleeding past 2 weeks. Denies pelvic pain, abdominal mass, weight change. TVUS shows endometrial_stripe 14 mm (PMB threshold >5 mm), heterogeneous, no mass-like distortion. CA-125 normal. PAP smear last age 60 (negative). BMI 34, T2DM × 8 yrs (Lynch / type-I endometrial risk profile). No HRT.

Workup steps (5)

MDT brief

MDT talk tree (3 steps)

#OwnerTopicAction
1pathologistSpecialist review Any suspicion requires biopsy — pathologist plans site selection, IHC panel, ancillary tests.
2radiologistSpecialist review Stage / restaging imaging + biopsy guidance — radiologist.
3surgical_oncologistSpecialist review Suspected solid tumor — resectability assessment, biopsy approach.

Skills (required) — mandatory virtual specialists (2)

  • Pathologist (general) required
    Any suspicion requires biopsy — pathologist plans site selection, IHC panel, ancillary tests.
  • Radiologist required
    Stage / restaging imaging + biopsy guidance — radiologist.

Skills (recommended) — for consideration (1)

  • Surgical oncologist recommended
    Suspected solid tumor — resectability assessment, biopsy approach.
Technical MDT skill metadata (3/16 activated in this plan)
All registered virtual specialists. ✓ — activated for this case; ○ — not activated (available for other clinical scenarios).
Specialistskill_idVersionLast reviewedSign-offsDomain
Cellular therapy specialist (CAR-T)cellular_therapy_specialistv0.1.02026-04-250cellular_therapy
Clinical pharmacistclinical_pharmacistv0.1.02026-04-250clinical_pharmacy
Hematologist / oncohematologisthematologistv0.1.02026-04-250hematology_oncology
Hematopathologist (lymphoma / leukemia / myeloma)hematopathologistv0.1.02026-04-250hematopathology
Infectious disease / hepatologyinfectious_disease_hepatologyv0.1.02026-04-250infectious_diseases
Medical oncologist (solid-tumor chemotherapist)medical_oncologistv0.1.02026-04-250solid_oncology
Molecular geneticist / molecular oncologistmolecular_geneticistv0.1.02026-04-250molecular_oncology
Palliative carepalliative_carev0.1.02026-04-250palliative_care
Pathologist (general)pathologistv0.1.02026-04-250pathology
Primary care / family physicianprimary_carev0.1.02026-04-250primary_care
Psycho-oncologistpsychologistv0.1.02026-04-250psychosocial
Radiation oncologistradiation_oncologistv0.1.02026-04-250radiation_oncology
Radiologistradiologistv0.1.02026-04-250diagnostic_imaging
Social worker / case managersocial_worker_case_managerv0.1.02026-04-250psychosocial
Surgical oncologistsurgical_oncologistv0.1.02026-04-250surgical_oncology
Transplant specialist (BMT)transplant_specialistv0.1.02026-04-250cellular_therapy