Structure the clinical context
The profile describes facts relevant to the decision: tumour type, stage, biomarkers, general condition and previous treatment.
OpenOnco
About OpenOnco
OpenOnco is an open clinical knowledge and rules project for oncology. This page collects the material that used to sit in separate top-menu links: examples, specifications and GitHub.
Our purpose
Make complex clinical decisions easier to understand
Cancer treatment rarely has a single obvious answer. Clinicians need to consider the diagnosis, stage, biomarkers, previous treatment and risks. Patients need to understand what to discuss at their appointment.
OpenOnco aims to make that process visible: show possible paths side by side, explain what influences the choice and link to sources. It supports preparation and discussion, rather than automatically prescribing treatment.
Our approach
A reproducible process for preparing a conversation with a clinician
Compare it with rules and sources
Rules use a versioned knowledge base. They explain why an option is considered, without guessing a drug or a dose.
Present results that can be checked
Users see options side by side, warnings and links to original sources, to prepare questions for a tumour board or oncologist.
The work behind it
The main effort goes into making results well supported
A structured knowledge base
The project maintainer records diseases, regimens, indications, warnings and sources as separate linked entities. Changes can then be versioned and checked, rather than getting lost in paragraphs.
Traceability at every step
Clinical claims have recorded provenance. Rules, results and public examples can be inspected rather than taken on trust.
Safety defines the boundaries
The system does not replace diagnosis, handle emergencies, calculate personalised doses or make decisions on behalf of a clinician.
Synthetic cases with rendered plans and diagnostic briefs. Use them to inspect how the engine explains decisions.
Open examples → SpecificationsThe authoritative project contract: charter, clinical content rules, schemas, ingestion and governance.
Read specs → GitHubSource code, knowledge-base YAML, issues, pull requests and public review history.
View repository →Local rule evaluation
Plan Builder downloads public engine and knowledge-base assets and evaluates clinical rules in your browser.
Server and provider processing
Tumor Board sends submitted text to the configured API server and may use a model provider. Check hosting and provider policies; do not submit identifying patient information.
Project shape
Open by default
Code is MIT-style; specifications and generated content are CC BY 4.0.
Synthetic public data
The public site ships no real patient records and no patient-specific private artifacts.
Clinical review gate
Clinical content needs reviewer sign-off before it can become trusted content.
Auditable automation
Rules, sources and rendered reasoning are visible instead of hidden behind a black box.
Current public corpus
103diseases
671red flags
834indications
407regimens
189algorithms
Current public build: v0.1.4, released 2026-05-06.
Next step
See what a traceable plan looks like
Try a synthetic example or open the plan builder. Do not enter personal patient information.
In memory of Danya
I dedicate all my work on OpenOnco to my friend Danya, who died of lymphoma in August 2026.