Heavy alcohol consumption — defined as >14 drinks/week (women) or >21 drinks/week (men) p...
Детермінований перегляд YAML-сутності з джерельної бази. Клінічний авторитет лишається за вказаними source ID та статусом клінічного sign-off.
| ID | RF-LIFESTYLE-ALCOHOL-CANCER-PREVENTION |
|---|---|
| Тип | Тривожна ознака |
| Статус | переглянуто 2026-05-18 | очікує клінічного підпису |
| Хвороби | DIS-BREAST DIS-CRC DIS-ESOPHAGEAL DIS-HCC |
| Джерела | SRC-NCCN-BCELL-2025 |
Походження тривожної ознаки
| Визначення | Heavy alcohol consumption — defined as >14 drinks/week (women) or >21 drinks/week (men) per US DHHS / WHO thresholds — OR cumulative lifetime alcohol use ≥40 drink-years. IARC Group 1 carcinogen — established etiological driver of head + neck squamous cell carcinoma (oral cavity + oropharynx + larynx + hypopharynx), esophageal SCC, hepatocellular carcinoma (via cirrhosis), colorectal cancer, female breast cancer (dose- response from ≥1 drink/day), and probably pancreatic + gastric. Alcohol-tobacco interaction is multiplicative for oral-pharyngeal- laryngeal-esophageal-SCC. Cessation / moderation produces meaningful cancer-incidence reduction over decades. Prevention- persona RedFlag (§20 v0.3 lifestyle pilot). |
|---|---|
| Клінічний напрям | investigate |
| Категорія | other |
Логіка спрацьовування
{
"any_of": [
{
"finding": "alcohol_heavy_use_above_threshold",
"value": true
},
{
"finding": "alcohol_lifetime_drink_years_ge_40",
"value": true
},
{
"finding": "alcohol_with_concurrent_tobacco_use",
"value": true
}
],
"type": "lab_value"
}
Нотатки
Prevention-persona RedFlag for heavy alcohol use. Engine routes to PreventionPlan recommending structured cessation/moderation counseling + pharmacotherapy + appropriate cancer screening (esophageal endoscopy for high-risk, breast cancer surveillance for women). STUB pending two-Clinical-Co-Lead signoff per CHARTER §6.1 dev-mode.
Де використовується
Indications
IND-LIFESTYLE-ALCOHOL-PREVENTION-CESSATION- IND-LIFESTYLE-ALCOHOL-PREVENTION-CESSATIONIND-LIFESTYLE-ALCOHOL-PREVENTION-OBSERVATION- IND-LIFESTYLE-ALCOHOL-PREVENTION-OBSERVATIONIND-LIFESTYLE-LOW-MEDITERRANEAN-DIET-PREVENTION-ADOPTION- IND-LIFESTYLE-LOW-MEDITERRANEAN-DIET-PREVENTION-ADOPTION