Nicotine transdermal patch
Детермінований перегляд YAML-сутності з джерельної бази. Клінічний авторитет лишається за вказаними source ID та статусом клінічного sign-off.
| ID | DRUG-NICOTINE-PATCH |
|---|---|
| Тип | Препарат |
| Синоніми | HabitrolNRT patchNicoDerm CQNicorette patchNicotine replacement therapy — patchNiquitinНікотиновий трансдермальний пластир |
| Статус | переглянуто 2026-05-18 | очікує клінічного підпису |
| Хвороби | Не вказано |
| Джерела | SRC-NCCN-BCELL-2025 |
Дані про препарат
| Клас | Nicotine replacement therapy (NRT) — transdermal nicotine |
|---|---|
| Механізм дії | Delivers controlled-release nicotine via skin absorption, producing steady plasma levels (~one-third to one-half of typical cigarette smoking) that substantially relieve craving and withdrawal symptoms while avoiding the rapid pulse + peak of inhaled smoking that drives reinforcement. First-line for tobacco cessation per USPSTF / AHCPR; combination with short-acting NRT (lozenge or gum) further improves quit rates vs. monotherapy. |
| Типове дозування | Patch-strength laddered to baseline cigarette exposure: - >10 cig/d: 21 mg/24h × 4-6 weeks, then 14 mg/24h × 2 weeks, then 7 mg/24h × 2 weeks (total 8-10 weeks) - ≤10 cig/d: start at 14 mg/24h Apply to clean, non-hairy upper-body skin; rotate site daily. Patch worn 24 h (or 16 h if vivid dreams problematic). Combination NRT (patch + short-acting lozenge or gum PRN cravings) preferred over monotherapy. |
| Зареєстровано в Україні | True |
| Відшкодовується НСЗУ | False |
| Остання перевірка для України | 2026-05-18 |
Нотатки
STUB — v0.2 prevention-workstream authoring; pending two-Clinical-Co-Lead signoff per CHARTER §6.1 dev-mode. First-line tobacco-cessation NRT; USPSTF Grade A. Combination NRT (patch as baseline + lozenge/gum PRN) improves abstinence vs. monotherapy. Safer than continued smoking even in cardiovascular disease — net benefit favors NRT in all but the most unstable cardiac patients. Source cited (SRC-NCCN-BCELL-2025) is closest in-KB until dedicated USPSTF/AHCPR/Cochrane NRT sources land in source-stub workstream.
Де використовується
Regimens
REG-NICOTINE-REPLACEMENT-COMBO- Combination NRT — patch + short-acting lozenge or gum PRN
Препарат
DRUG-NICOTINE-GUM- Nicotine gum (NRT)