Nicotine transdermal patch
Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.
| ID | DRUG-NICOTINE-PATCH |
|---|---|
| Type | Drug |
| Aliases | HabitrolNRT patchNicoDerm CQNicorette patchNicotine replacement therapy — patchNiquitinНікотиновий трансдермальний пластир |
| Status | reviewed 2026-05-18 | pending_clinical_signoff |
| Diseases | None declared |
| Sources | SRC-NCCN-BCELL-2025 |
Drug Facts
| Class | Nicotine replacement therapy (NRT) — transdermal nicotine |
|---|---|
| Mechanism | Delivers controlled-release nicotine via skin absorption, producing steady plasma levels (~one-third to one-half of typical cigarette smoking) that substantially relieve craving and withdrawal symptoms while avoiding the rapid pulse + peak of inhaled smoking that drives reinforcement. First-line for tobacco cessation per USPSTF / AHCPR; combination with short-acting NRT (lozenge or gum) further improves quit rates vs. monotherapy. |
| Typical dosing | Patch-strength laddered to baseline cigarette exposure: - >10 cig/d: 21 mg/24h × 4-6 weeks, then 14 mg/24h × 2 weeks, then 7 mg/24h × 2 weeks (total 8-10 weeks) - ≤10 cig/d: start at 14 mg/24h Apply to clean, non-hairy upper-body skin; rotate site daily. Patch worn 24 h (or 16 h if vivid dreams problematic). Combination NRT (patch + short-acting lozenge or gum PRN cravings) preferred over monotherapy. |
| Ukraine registered | True |
| NSZU reimbursed | False |
| Ukraine last verified | 2026-05-18 |
Notes
STUB — v0.2 prevention-workstream authoring; pending two-Clinical-Co-Lead signoff per CHARTER §6.1 dev-mode. First-line tobacco-cessation NRT; USPSTF Grade A. Combination NRT (patch as baseline + lozenge/gum PRN) improves abstinence vs. monotherapy. Safer than continued smoking even in cardiovascular disease — net benefit favors NRT in all but the most unstable cardiac patients. Source cited (SRC-NCCN-BCELL-2025) is closest in-KB until dedicated USPSTF/AHCPR/Cochrane NRT sources land in source-stub workstream.
Used By
Drug
DRUG-NICOTINE-GUM- Nicotine gum (NRT)
Regimens
REG-NICOTINE-REPLACEMENT-COMBO- Combination NRT — patch + short-acting lozenge or gum PRN