HCV-Status (Anti-HCV-Antikörper-Screening)
Deterministische Ansicht der Quelle YAML Entität. Klinische Autorität bleibt mit den zitierten Quell-IDs und Rezensenten Sign-off Zustand.
| ID | BIO-HCV-STATUS |
|---|---|
| Art | Biomarker |
| Aliase | HCV-SerologieHepatitis C-ScreeningHepatitis C-VirusstatusAnti-HCV-VerfahrenСтатус HCV (антитіла анти-HCV) |
| Status | reviewed 2026-04-26 | pending_clinical_signoff |
| Erkrankungen | DIS-DLBCL-NOS DIS-HCC DIS-MM DIS-NODAL-MZL DIS-SPLENIC-MZL |
| Quellen | SRC-EASL-HCV-2023 SRC-NCCN-BCELL-2025 |
Biomarker-Fakten
| Biomarker-Typ | viral_serology |
|---|---|
| Messung | VerfahrenAnti-HCV antibody (third-generation EIA). Reflex to BIO-HCV-RNA (quantitative PCR) when anti-HCV+ to distinguish active infection (RNA detectable) from resolved / cleared (RNA undetectable, antibody persists for life). Einheitencategorical: anti-HCV+ | anti-HCV- |
| Verwandte Biomarker | BIO-HCV-RNA BIO-HBV-STATUS BIO-HIV-STATUS |
Anmerkungen
Screening test; positive result is necessary but not sufficient evidence of active HCV (false positives in autoimmune disease, cleared infections retain antibodies indefinitely). Active infection requires BIO-HCV-RNA detectable; rules engine should branch on HCV-RNA positivity, not antibody alone, for any DAA / treatment decision. Currently consumed by: ALGO-MM-1L (etiology rail — coordinate DAA with hepatologist if HCV+). Companion biomarker BIO-HCV-RNA carries the quantitative load and drives the HCV-MZL etiologically-driven algorithm. STATUS is the cheap screening; RNA is the actionable confirmation. reviewer_signoffs: 0 # STUB — pending two Clinical Co-Lead approvals
Verwendet von
Algorithmen
ALGO-HCV-MZL-2L- ALGO-HCV-MZL-2L
Biomarker
BIO-HBV-STATUS- HBV-Status (HBsAg + Anti-HBc-Serologie)BIO-HCV-RNA-QUANTITATIVE-MONITORING- HCV-RNA quantitative — virale Belastungsüberwachung während einer direkt wirkenden antiviralen (DAA) TherapieBIO-HIV-STATUS- HIV-Status (4. Gen Ag/Ab-Combo-Screening)
Kapitel des Handbuchs
HB-DLBCL-1L- Diffuse große B-Zell-Lymphom: First-Line-Reinigung
Anwendungsgebiet
IND-DLBCL-1L-POLA-R-CHP- IND-DLBCL-1L-POLA-R-CHPIND-DLBCL-1L-RCHOP- IND-DLBCL-1L-RCHOPIND-HCC-SYSTEMIC-1L-ATEZO-BEV- IND-HCC-SYSTEMIC-1L-ATEZO-BEVIND-MM-1L-DARA-RD- IND-MM-1L-DARA-RDIND-MM-1L-DVRD- IND-MM-1L-DVRDIND-NMZL-1L-HCV-POSITIVE- IND-NMZL-1L-HCV-POSITIVEIND-SMZL-1L-HCV-POSITIVE- IND-SMZL-1L-HCV-POSITIVE
Fragebogen
QUEST-DLBCL-NOS-1L-STUB- Diffuse Großes B-Zell-Lymphom, nicht anders angegeben — erste ZeileQUEST-HCC-1L-STUB- Leberzelluläres Karzinom — erste ZeileQUEST-NODAL-MZL-1L-STUB- Nodal Marginal Zone Lymphom — erste ZeileQUEST-SPLENIC-MZL-1L-STUB- Milzrandzonenlymphom — erste Zeile