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Onco Wiki / Тривожна ознака

High habitual intake of sugar-sweetened beverages (SSBs) — sodas, fruit drinks, sports dr...

Детермінований перегляд YAML-сутності з джерельної бази. Клінічний авторитет лишається за вказаними source ID та статусом клінічного sign-off.

IDRF-LIFESTYLE-SUGARY-BEVERAGES-PREVENTION
ТипТривожна ознака
Статуспереглянуто 2026-05-19 | очікує клінічного підпису
ХворобиDIS-BREAST DIS-CRC DIS-ENDOMETRIAL DIS-PDAC
ДжерелаSRC-NCCN-BREAST-2025 SRC-USPSTF-CRC-2021

Походження тривожної ознаки

ВизначенняHigh habitual intake of sugar-sweetened beverages (SSBs) — sodas, fruit drinks, sports drinks, sweetened teas/coffees — ≥1 serving (~250 mL) per day. Associated with increased risk of obesity-related cancers including colorectal cancer (RR ~1.2-1.3 in women with ≥2 servings/ day per Nurses' Health Study II; Hur et al. Gut 2021), pancreatic cancer (modest signal in some cohorts), early-onset CRC (under age 50 — Hur 2021 reported ~RR 2.2 for ≥2 servings/day vs <1/wk), and endometrial + post-menopausal breast cancer via obesity pathway. Mechanism: rapid glycemic load → insulin/IGF-1 axis activation + weight gain + adiposity. SSBs are the largest single dietary source of added sugar in many populations. Risk modifiable via substitution with water, unsweetened beverages, low-calorie sweeteners (though recent evidence raises questions about non-nutritive sweetener safety — see controversies)....
Клінічний напрямinvestigate
Категоріяother

Логіка спрацьовування

{
  "any_of": [
    {
      "finding": "ssb_daily_consumption_ge_1",
      "value": true
    },
    {
      "finding": "ssb_consumption_ge_2_per_day",
      "value": true
    },
    {
      "finding": "early_onset_crc_risk_diet",
      "value": true
    }
  ],
  "type": "lab_value"
}

Нотатки

Prevention-persona RedFlag for sugar-sweetened beverage habitual intake. Counseling: substitute water/unsweetened beverages; reduce gradually if abrupt cessation difficult; assess for contribution to weight gain + glycemic dysregulation. Modest individual RR but very common exposure → large absolute population-attributable fraction. STUB pending two-Co-Lead signoff per CHARTER §6.1 dev-mode.

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Indications