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Carcinoma de células escamosas do canal anal

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IDDIS-ANAL-SCC
TipoDoença
Alegais
CSC do canal analCarcinoma analCarcinoma de células escamosas anal (CSC anal)Câncer do ânusSCCACarcinoma de células escamosas do ânusПлоскоклітинний рак анального каналу
Estadoreviewed 2026-05-04 | pending_clinical_signoff
DoençasNenhuma declaração
FontesNenhuma declaração

Informational support. All recommendations must be verified by a qualified oncologist. Engineering checks are not clinical validation or treatment approval.

Fonte YAML

icd_10C21.0
icd_o_3_morphology8070/3
icd_o_3_topography["C21.0", "C21.1", "C21.2"]
oncotree_codeANSC

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Anal SCC is HPV-driven (90%) and highly curable in locally advanced stages (~75-85%) with organ-preserving chemoradiation. The Nigro protocol (mitomycin C + 5-FU + RT) is NCCN Category 1 — APR is NOT standard initial treatment. Response assessment at 8-11 weeks post-CRT; confirm residual disease by biopsy before salvage APR. HIV+ patients require same CRT with antiretroviral optimization. Screening: high-resolution anoscopy for HIV+ patients and MSM is recommended.

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