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Carcinoma de células escamosas do pénis

Visão determinística da entidade fonte YAML. A autoridade clínica permanece com os IDs de fonte citados e estado de assinatura do revisor.

IDDIS-PENILE-SCC
TipoDoença
Alegais
Câncer do pénisCSC do pénis associado ao HPVPênis CCECâncer do pénisПлоскоклітинна карцинома пенісу
Estadoreviewed 2026-05-18 | pending_clinical_signoff
DoençasNenhuma declaração
FontesSRC-IARC-MONO-100B-2012 SRC-NCCN-BLADDER-2025

Informational support. All recommendations must be verified by a qualified oncologist. Engineering checks are not clinical validation or treatment approval.

Fonte YAML

icd_o_3_morphology8070/3
icd_o_3_topography["C60"]
icd_10C60
who_classificationWHO Urinary and Male Genital Tumours 5th ed (2022): Penile squamous cell carcinoma (HPV-associated + HPV-independent subtypes)

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Two biological subgroups (HPV-driven vs HPV-independent) managed similarly anatomically. Treatment: early-stage (Tis, Ta, T1a) — organ-sparing approaches (topical 5-FU / imiquimod for Tis; CO2- laser or wide local excision for T1a; glansectomy for selected T2); advanced primary (T2-T4) — partial / total penectomy; inguinal nodal management — dynamic sentinel node biopsy or modified inguinal lymphadenectomy per cN0 vs cN+ status (highly morbid, complications common); metastatic — cisplatin + 5-FU OR TIP (paclitaxel + ifosfamide + cisplatin) per EAU; pembrolizumab in MSI-H subset. HPV vaccination of boys (Gardasil-9) is the primary prevention modality alongside neonatal circumcision discussion.

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