Pituitary adenoma (typically nonfunctioning macroadenoma) causing compressive mass effect...
Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.
| ID | RF-PITUITARY-MASS-EFFECT-VISUAL-COMPROMISE |
|---|---|
| Type | Red flag |
| Status | reviewed 2026-07-11 | pending_clinical_signoff |
| Diseases | DIS-PITUITARY-ADENOMA |
| Sources | SRC-NCCN-CNS-2025 |
Red Flag Origin
| Definition | Pituitary adenoma (typically nonfunctioning macroadenoma) causing compressive mass effect — visual field deficit / optic chiasm compression, new cranial neuropathy, or hypopituitarism attributable to sellar/suprasellar compression — indicating surgical resection is required rather than observation. |
|---|---|
| Clinical direction | intensify |
| Category | organ-dysfunction |
| Shifts algorithm | ALGO-PITUITARY-ADENOMA-1L |
Trigger Logic
{
"any_of": [
{
"finding": "visual_field_deficit",
"value": true
},
{
"finding": "optic_chiasm_compression",
"value": true
},
{
"finding": "pituitary_mass_effect_symptoms",
"value": true
},
{
"condition": "Macroadenoma with radiographic optic chiasm/nerve compression, new cranial neuropathy, or hypopituitarism attributable to mass effect"
}
],
"type": "symptom_composite"
}
Notes
STUB pending clinical co-lead signoff (CHARTER §6.1 — dev-mode-exempted). Per the Disease narrative, nonfunctioning pituitary adenoma is managed with surgery only for mass effect / visual compromise; asymptomatic non-compressive NFPA is appropriate for observation with surveillance imaging and is deliberately not modeled as an active-therapy Indication in this KB (mirrors the existing "active surveillance, not a separate indication" pattern used in ALGO-GI-NET-ADVANCED-1L). "visual_field_deficit", "optic_chiasm_compression", and "pituitary_mass_effect_symptoms" are new free-form finding keys — no engine-side data-collection wiring confirmed to exist yet for these keys; the `condition:` free-text leaf in the trigger preserves the clinical criterion regardless of finding wiring status, consistent with existing KB precedent (e.g. RF/algorithm notes in ALGO-RCC-METASTATIC-1L for unwired finding keys).
Used By
Algorithms
ALGO-PITUITARY-ADENOMA-1L- ALGO-PITUITARY-ADENOMA-1L
Indications
IND-PITUITARY-ADENOMA-1L-NFPA-SURGERY-MASS-EFFECT- IND-PITUITARY-ADENOMA-1L-NFPA-SURGERY-MASS-EFFECT