Documented occupational vinyl chloride monomer (VCM) exposure — historically in PVC manuf...

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

ID	`RF-OCC-VINYL-CHLORIDE-MALIGNANCY-PREVENTION`
Type	Red flag
Status	reviewed 2026-05-18 \| pending_clinical_signoff
Diseases	`DIS-HCC`
Sources	`SRC-AASLD-HCC-2023` `SRC-NCCN-BCELL-2025`

Red Flag Origin

Definition	Documented occupational vinyl chloride monomer (VCM) exposure — historically in PVC manufacturing, pre-1974 regulations. IARC Group 1 carcinogen — pathognomonic for hepatic angiosarcoma (~RR ~100); also implicated in HCC, brain tumors, lung. Pre-regulation cohort still at residual risk decades post-exposure cessation. Prevention-persona RedFlag (§20 v0.3 occupational).
Clinical direction	investigate
Category	other

Trigger Logic

{
  "any_of": [
    {
      "finding": "occupational_vinyl_chloride_exposure_documented",
      "value": true
    },
    {
      "finding": "occupational_pvc_manufacturing_pre_regulation",
      "value": true
    }
  ],
  "type": "lab_value"
}

Notes

Prevention-persona RedFlag for vinyl chloride → hepatic angiosarcoma / HCC. Pre-1974 PVC workers still at residual risk. STUB pending two-Co-Lead signoff.

Used By

Indications

IND-OCC-VINYL-CHLORIDE-PREVENTION-OBSERVATION - IND-OCC-VINYL-CHLORIDE-PREVENTION-OBSERVATION
IND-OCC-VINYL-CHLORIDE-PREVENTION-SURVEILLANCE - IND-OCC-VINYL-CHLORIDE-PREVENTION-SURVEILLANCE