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Active tobacco smoking (current smoker OR cessation <15 years) OR smokeless tobacco use O...

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

IDRF-LIFESTYLE-TOBACCO-CANCER-PREVENTION
TypeRed flag
Statusreviewed 2026-05-18 | pending_clinical_signoff
DiseasesDIS-AML DIS-HCC DIS-NSCLC DIS-PDAC DIS-SCLC DIS-UROTHELIAL
SourcesSRC-NCCN-BCELL-2025

Red Flag Origin

DefinitionActive tobacco smoking (current smoker OR cessation <15 years) OR smokeless tobacco use OR significant secondhand smoke exposure. IARC Group 1 carcinogen — established etiological driver of lung cancer (NSCLC + SCLC; population-attributable fraction ~80-90%), urothelial bladder cancer, head + neck squamous cell carcinoma, oropharyngeal, laryngeal, esophageal SCC, pancreatic cancer, kidney (RCC), cervical, acute myeloid leukemia (component cause), and others (~20 cancer types per US Surgeon General reports). Tobacco cessation is the single highest-impact modifiable cancer-risk-factor intervention. Prevention- persona RedFlag (§20 v0.3 lifestyle pilot).
Clinical directioninvestigate
Categoryother

Trigger Logic

{
  "any_of": [
    {
      "finding": "tobacco_status_current_smoker",
      "value": true
    },
    {
      "finding": "tobacco_pack_years_ge_20",
      "value": true
    },
    {
      "finding": "tobacco_cessation_within_15y",
      "value": true
    },
    {
      "finding": "smokeless_tobacco_use",
      "value": true
    },
    {
      "finding": "significant_secondhand_smoke_exposure",
      "value": true
    }
  ],
  "type": "lab_value"
}

Notes

Prevention-persona RedFlag for active tobacco use. Highest-impact modifiable cancer-risk-factor intervention. Engine routes to PreventionPlan recommending structured cessation counseling + pharmacotherapy + LDCT lung screening if USPSTF-eligible. STUB pending two-Clinical-Co-Lead signoff per CHARTER §6.1 dev-mode.

Used By

Indications