Habitual low dietary fibre intake (<15 g/day; WCRF/AICR convincing- evidence threshold is...
Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.
| ID | RF-LIFESTYLE-LOW-FIBER-CRC-PREVENTION |
|---|---|
| Type | Red flag |
| Status | reviewed 2026-05-18 | pending_clinical_signoff |
| Diseases | DIS-CRC |
| Sources | SRC-NCCN-BCELL-2025 SRC-NCCN-COLON-2025 |
Red Flag Origin
| Definition | Habitual low dietary fibre intake (<15 g/day; WCRF/AICR convincing- evidence threshold is ≥30 g/day, IOM adequate intake 25 g/day female / 38 g/day male). WCRF/AICR Continuous Update Project rates dietary fibre as "convincing" protective for colorectal cancer — each 10 g/day of total fibre intake reduces CRC risk by ~10% (RR ~0.90). Mechanisms: faecal bulking + reduced transit time + microbiota-derived short-chain fatty acids (butyrate) supporting colonocyte differentiation + dilution of luminal carcinogens. Whole-grain, vegetable, fruit, and pulse fibre sources show consistent inverse association with CRC incidence in large prospective cohorts (EPIC, NHS, HPFS). Prevention- persona RedFlag (§20 v0.3 diet pilot, 2026-05-18). |
|---|---|
| Clinical direction | investigate |
| Category | other |
Trigger Logic
{
"any_of": [
{
"finding": "dietary_fiber_intake_lt_15g_per_day",
"value": true
},
{
"finding": "low_whole_grain_intake",
"value": true
},
{
"finding": "low_vegetable_fruit_intake",
"value": true
}
],
"type": "lab_value"
}
Notes
Prevention-persona RedFlag for low dietary fibre intake (<15 g/day). WCRF/AICR convincing-evidence rating for CRC. Effect size modest individually but population-attributable fraction non-trivial (low fibre intake is endemic in Western diets). Engine routes to PreventionPlan recommending dietary counseling + USPSTF-cadence CRC screening. STUB pending two-Clinical-Co-Lead signoff per CHARTER §6.1 dev-mode.
Used By
Indications
IND-LIFESTYLE-LOW-FIBER-CRC-PREVENTION-DIETARY- IND-LIFESTYLE-LOW-FIBER-CRC-PREVENTION-DIETARYIND-LIFESTYLE-LOW-FIBER-CRC-PREVENTION-OBSERVATION- IND-LIFESTYLE-LOW-FIBER-CRC-PREVENTION-OBSERVATION