Chronic immunosuppression for solid-organ transplant or post-allogeneic HSCT. Elevated ri...

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

ID	`RF-IATROGENIC-TRANSPLANT-IMMUNOSUPPRESSION-PREVENTION`
Type	Red flag
Status	reviewed 2026-05-18 \| pending_clinical_signoff
Diseases	`DIS-BURKITT` `DIS-CERVICAL` `DIS-DLBCL-NOS`
Sources	`SRC-NCCN-BCELL-2025` `SRC-NCCN-CERVICAL-2025`

Red Flag Origin

Definition	Chronic immunosuppression for solid-organ transplant or post-allogeneic HSCT. Elevated risk of: post-transplant lymphoproliferative disorder (PTLD, EBV-driven), squamous cell carcinoma + basal cell carcinoma (skin), Kaposi sarcoma (HHV-8), non-melanoma + melanoma skin cancers, anal cancer (HPV-driven), cervical cancer, oropharyngeal cancer, HCC (HBV/HCV reactivation in transplant context). Prevention-persona RedFlag.
Clinical direction	investigate
Category	other

Trigger Logic

{
  "any_of": [
    {
      "finding": "post_solid_organ_transplant_immunosuppression",
      "value": true
    },
    {
      "finding": "post_allogeneic_hsct_chronic_immunosuppression",
      "value": true
    }
  ],
  "type": "lab_value"
}

Notes

Prevention-persona RedFlag for transplant immunosuppression. Engine routes to PreventionPlan with intensive surveillance + reduce immunosuppression discussion + targeted screening. STUB.

Used By

Indications

IND-IATROGENIC-TRANSPLANT-IMMUNOSUPPRESSION-LONGTERM-PREVENTION-SURVEILLANCE - IND-IATROGENIC-TRANSPLANT-IMMUNOSUPPRESSION-LONGTERM-PREVENTION-SURVEILLANCE
IND-IATROGENIC-TRANSPLANT-IMMUNOSUPPRESSION-PREVENTION-OBSERVATION - IND-IATROGENIC-TRANSPLANT-IMMUNOSUPPRESSION-PREVENTION-OBSERVATION
IND-IATROGENIC-TRANSPLANT-IMMUNOSUPPRESSION-PREVENTION-SURVEILLANCE - IND-IATROGENIC-TRANSPLANT-IMMUNOSUPPRESSION-PREVENTION-SURVEILLANCE

Red flag

RF-IATROGENIC-TRANSPLANT-IMMUNOSUPPRESSION-LONGTERM-PREVENTION - Solid-organ transplant recipient on chronic immunosuppression ≥3 years post-transplant, b...