Sustained domestic exposure to indoor combustion emissions from high- temperature cooking...

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

ID	`RF-ENVIRONMENTAL-FRYING-EMISSIONS-PREVENTION`
Type	Red flag
Status	reviewed 2026-05-19 \| pending_clinical_signoff
Diseases	`DIS-NSCLC`
Sources	`SRC-NCCN-BCELL-2025` `SRC-NCCN-NSCLC-2025`

Red Flag Origin

Definition	Sustained domestic exposure to indoor combustion emissions from high- temperature cooking — particularly stir-frying and deep-frying with vegetable oils at temperatures sufficient for thermal-degradation product release — in poorly ventilated kitchens. The epidemiologic signal is strongest among East Asian women cooking for the household on traditional gas / coal / solid-fuel stoves with absent or inadequate range-hood exhaust ventilation. IARC Monograph 95 (2010, "Household Use of Solid Fuels and High-Temperature Frying") classified emissions from high-temperature frying as Group 2A (probably carcinogenic to humans) — limited evidence in humans (Chinese / Taiwanese / Singaporean case-control studies showing elevated lung-cancer risk in non-smoking women whose kitchen ventilation was inadequate, dose-response by hours/day of cooking and years of exposure), sufficient evidence in experim...
Clinical direction	investigate
Category	other

Trigger Logic

{
  "any_of": [
    {
      "finding": "domestic_high_temperature_cooking_inadequate_ventilation",
      "value": true
    },
    {
      "finding": "domestic_stir_fry_daily_decades_exposure",
      "value": true
    },
    {
      "finding": "indoor_combustion_frying_emissions_chronic",
      "value": true
    }
  ],
  "type": "lab_value"
}

Notes

Prevention-persona RedFlag — v0.3 IARC 2A probable-carcinogen batch (2026-05-19). IARC Group 2A probable — limited human evidence; clinical recommendation more conservative than Group 1. IARC Monograph 95 (2010) is the canonical evidence anchor and is NOT yet a separate SRC entity in KB; cited in notes only. Population-specific framing: the lung-cancer signal is most characteristic in East Asian non-smoking women (Chinese / Taiwanese / Singaporean / Korean / Vietnamese populations) where cooking-emissions exposure is sustained over decades on traditional cookware in homes with limited ventilation. The same exposure pattern in Western kitchens (different cooking-style mix, generally better ventilation, lower cumulative dose) carries less population-level evidence — but the IARC 2A classification applies wherever high-temperature frying with inadequate ventilation occurs. Engine routes to 2-track PreventionPlan: (a) IND-ENVIRONMENTAL-FRYING-EMISSIONS-PREVENTION-INTENSIFIED- SURVEILLANCE (standard) — ventilation-upgrade counseling, cooking-method counseling, risk-adjusted LDCT consideration when clustering with other lung-cancer risk factors. (b) IND-ENVIRONMENTAL-FRYING-EMISSIONS-PR...

Used By

Indications

IND-ENVIRONMENTAL-FRYING-EMISSIONS-PREVENTION-INTENSIFIED-SURVEILLANCE - IND-ENVIRONMENTAL-FRYING-EMISSIONS-PREVENTION-INTENSIFIED-SURVEILLANCE
IND-ENVIRONMENTAL-FRYING-EMISSIONS-PREVENTION-OBSERVATION - IND-ENVIRONMENTAL-FRYING-EMISSIONS-PREVENTION-OBSERVATION