Diagnostic lineage immunohistochemistry marker panel
Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.
| ID | BIO-DIAGNOSTIC-IHC-LINEAGE |
|---|---|
| Type | Biomarker |
| Aliases | AE1/AE3AFPALKAMACRARARID1AATRXATRX lossAnnexin A1BAP1BAP1 lossBCL2BCL6BRG1BRG1 lossBerEP4CAIXCAM5.2CCND1CD10CD117CD11cCD123CD138CD15CD163CD1aCD2CD20CD23CD3CD30CD31CD34CD4CD45CD5CD56CD68CD7CD79aCD8CDK4CDX2CEACK AE1/AE3CK19CK20CK5CK5/6CK6CK7CK8/18D2-40DBA44DOG1DPC4Diagnostic lineage IHC markersEBEREBER ISHEMAERERGEpCAMFLI1GATA3GCDFP-15GFAPGPC3HMB-45HMB45HNF1-betaHNF1BHPV ISHIDH1 R132HINI1INI1 lossINSM1IRF4KITKi-67Ki67LCAMART-1MDM2MITFMOC31MPOMSAMTAPMTAP lossMUC1MUC2MUC5ACMUC6MUM1Melan-AMyoD1NCAMNKX3.1Napsin AOCT3/4OCT4OLIG2P504SPAX5PAX8PLAPPRPRAMEPSAPSAPRCC MaRCC markerS-100S100SALL4SATB2SMASMAD4SMARCA4SMARCB1SOX10SOX11STAT6TCL1TLE1TRAPTRPS1TTF-1TTF1TdTWT1androgen receptorannexin-1beta cateninbeta-cateninbeta-hCGcalcitonincaldesmoncalretinincarbonic anhydrase IXchromograninchromogranin Aclaudin-4cyclin D1cytokeratincytokeratin 20cytokeratin 5/6cytokeratin 7cytokeratin AE1/AE3desminepithelial membrane antigenestrogen receptorfactor VIIIglypican-3gross cystic disease fluid protein 15h-caldesmonhCGkappalambdalangerinleukocyte common antigenmammaglobinmonoclonal CEAmuscle specific actinmyeloperoxidasemyogeninp16p40p53p63pan CKpan-CKpan-cytokeratinpancytokeratinpodoplaninpolyclonal CEAprogesterone receptorprostate specific antigenprostatic acid phosphatasesmooth muscle actinsynaptophysinthrombomodulinthyroglobulinthyroid transcription factor-1uroplakinuroplakin IIuroplakin IIIvillin |
| Status | reviewed 2026-05-08 |
| Diseases | None declared |
| Sources | SRC-ACS-BIOPSY-SPECIAL-TESTS SRC-HEMONC-PATHOLOGY |
Biomarker Facts
| Biomarker type | protein_expression_ihc |
|---|---|
| Measurement | MethodImmunohistochemistry or in situ hybridization on FFPE tissue as part of a diagnostic lineage/differentiation panel Unitscategorical staining pattern or expression status |
| Related biomarkers | None declared |
Notes
Composite vocabulary entry for diagnostic lineage and differentiation IHC markers. These markers support histogenesis, site-of-origin, lymphoma immunophenotype, neuroendocrine differentiation, melanoma lineage, mesothelial lineage, sarcoma lineage, and germ-cell differentiation. They should be accepted by free-text case parsing as biopsy context, but should not be interpreted as variant-level actionability or used alone to select targeted systemic therapy.
Used By
No reverse references found in the YAML corpus.