Infection par le VIH (sérologie positive) chez un individu sans sida ou VIH...
Vue déterministe de l'entité source de la LJAM. L'autorité clinique demeure avec les ID de la source cités et l'état d'approbation de l ́examinateur.
| ID | RF-CHRONIC-HIV-MALIGNANCY-PREVENTION |
|---|---|
| Type | Signal d’alerte |
| État | reviewed 2026-05-18 | pending_clinical_signoff |
| Maladies | DIS-DLBCL-NOS |
| Sources | SRC-NCCN-BCELL-2025 SRC-NIH-AIDS-2024 |
Origine du drapeau rouge
| Définition | HIV infection (positive serology) in an individual without a current AIDS-defining or HIV-associated malignancy diagnosis. IARC Group 1 carcinogen (HIV-1) — drives elevated risk of Kaposi sarcoma (KS), non-Hodgkin lymphoma (especially DLBCL, Burkitt, PCNSL), invasive cervical cancer (AIDS-defining trio), and elevated incidence of Hodgkin lymphoma, anal cancer, HCC (via HCV co-infection), and oropharyngeal cancer. Effective antiretroviral therapy (ART) with durable virological suppression substantially reduces all AIDS-defining malignancy incidence and modestly reduces non-AIDS-defining cancer incidence. Prevention-persona RedFlag (§20 ratification 2026-05-18). |
|---|---|
| Direction clinique | enquêter |
| Catégorie | autres |
Logique de déclenchement
{
"any_of": [
{
"finding": "hiv_status",
"value": "positive"
},
{
"finding": "hiv_serology",
"value": "positive"
}
],
"type": "lab_value"
}
Notes
Prevention-persona RedFlag for HIV-associated cancer prevention. Fires on positive HIV serology in patient without AIDS-defining or HIV-associated malignancy. Engine routes to PreventionPlan recommending durable ART suppression (per IND-CHRONIC-HIV-PREVENTION-ART) + cancer screening cadence (annual anal cytology in MSM/HIV+; q3-yearly cervical Pap in WLHIV; opportunistic Kaposi/oral hairy leukoplakia visual screening). STUB pending Co-Lead review. Cancer scope: anchored to DIS-DLBCL-NOS as the canonical HIV-associated NHL. KS, cervical, anal, Hodgkin, HCC are also HIV-associated; covered via screening recommendations in the ART indication rationale rather than discrete Disease anchors (until DIS-KAPOSI etc. land in v0.2-A authoring backlog).
Utilisé par
Indication
IND-CHRONIC-HIV-PREVENTION-ART- IND-CHRONIC-HIV-PREVENTION-ARTIND-CHRONIC-HIV-PREVENTION-OBSERVATION- IND-CHRONIC-HIV-PREVENTION-OBSERVATIONIND-UNIVERSAL-IMMUNOCOMPROMISED-PREVENTION-STRATIFIED-SCREENING- IND-UNIVERSAL-IMMUNOCOMPROMISED-PREVENTION-STRATIFIED-SCREENING
Signal d’alerte
RF-CHRONIC-HHV8-MALIGNANCY-PREVENTION- la séropositivité HHV-8 (herpèsvirus associé au sarcome de Kaposi, KSHV) dans une immunodétermination...RF-CHRONIC-HIV-HBV-COINFECTION-PREVENTION- Co-infection concomitante VIH + VHB (VIH positive et AgHBs positive ≥6 mois OU ADN-VHB...RF-UNIVERSAL-IMMUNOCOMPROMISED-CANCER-RISK- immunosuppression chronique ≥ 1 an — l'un des cas suivants: a) VIH non traité ou traité par CD4 nadir <...