Adénome de la pituitaire
Vue déterministe de l'entité source de la LJAM. L'autorité clinique demeure avec les ID de la source cités et l'état d'approbation de l ́examinateur.
| ID | DIS-PITUITARY-ADENOMA |
|---|---|
| Type | Maladie |
| Alias | Adénome de corticotropheAdénome hypophysaire associé au MEN1Adénome hypophysaire non fonctionnantPitNETTumeur neuroendocrine pituitaireProlactinomeAdénome de somatotropheАденома гіпофіза |
| État | reviewed 2026-05-18 | pending_clinical_signoff |
| Maladies | Aucune déclaration |
| Sources | SRC-NCCN-CNS-2025 SRC-NCCN-NET-2025 |
Informational support. All recommendations must be verified by a qualified oncologist. Engineering checks are not clinical validation or treatment approval.
| icd_o_3_morphology | 8272/0 |
|---|---|
| icd_o_3_topography | ["C75.1"] |
| icd_10 | D35.2 |
| who_classification | WHO Endocrine and Neuroendocrine Tumours 5th ed (2022) + CNS 5th ed (2021): Pituitary neuroendocrine tumor (PitNET) lineage-based classification — lactotroph / somatotroph / corticotroph / thyrotroph / gonadotroph / null-cell |
Notes
Functional adenomas classified by lineage / hormone hypersecretion; treatment is endocrine-cohort-specific: prolactinoma — dopamine agonists (cabergoline > bromocriptine) first-line, surgery for resistant / intolerant; somatotroph (acromegaly) — transsphenoidal surgery first-line, somatostatin analogs (octreotide LAR, lanreotide, pasireotide LAR), GH-receptor antagonist (pegvisomant) for residual; corticotroph (Cushing disease) — surgery, pasireotide, ketoconazole / metyrapone / osilodrostat for cortisol control; nonfunctioning — surgery for mass effect / visual compromise. MEN1 carriers: cascade screening from age 5 (prolactin + IGF-1 + serum Ca + intact PTH + fasting gastrin + pituitary MRI per protocol).
Utilisé par
Algorithmes
ALGO-MEN1-CARRIER-SURVEILLANCE- ALGO-MEN1-CARRIER-SURVEILLANCEALGO-PITUITARY-ADENOMA-1L- ALGO-PITUITARY-ADENOMA-1L
Maladie
DIS-PARATHYROID-CARCINOMA- Carcinome parathyroïdienDIS-PITUITARY-BLASTOMA- Blastome pituitaire
Médicament
DRUG-CABERGOLINE- Cabergoline.DRUG-PASIREOTIDE- Pasireotide
Indication
IND-PITUITARY-ADENOMA-1L-ACROMEGALY-SURGERY-SSA- IND-PITUITARY-ADENOMA-1L-ACROMEGALY-SURGERY-SSAIND-PITUITARY-ADENOMA-1L-CUSHING-SURGERY-MEDICAL- IND-PITUITARY-ADENOMA-1L-CUSHING-SURGERY-MEDICALIND-PITUITARY-ADENOMA-1L-NFPA-SURGERY-MASS-EFFECT- IND-PITUITARY-ADENOMA-1L-NFPA-SURGERY-MASS-EFFECTIND-PITUITARY-ADENOMA-1L-PROLACTINOMA-CABERGOLINE- IND-PITUITARY-ADENOMA-1L-PROLACTINOMA-CABERGOLINE
Signal d’alerte
RF-PITUITARY-MASS-EFFECT-VISUAL-COMPROMISE- Adénome pituitaire (généralement non fonctionnant macroadénome) causant un effet de masse compressive...
Protocole thérapeutique
REG-CABERGOLINE-PROLACTINOMA- Cabergoline pour le prolactinome (agoniste de la dopamine, première ligne)REG-PASIREOTIDE-CUSHING- Pasireotide pour la maladie de Cushing (thérapie médicale dirigée par l'ipophyse)REG-SSA-ACROMEGALY- analogue de la somatostatine pour l'acromégalie (lanreotide de première génération SSA; pasireotide pour SS...