Onco Wiki / Bandera roja

APL patient with positive HBV / HCV / HIV serology, latent TB, or active uncontrolled inf...

Vista determinista de la entidad fuente YAML. La autoridad clínica sigue con los ID de fuente citados y estado de firma del revisor.

Origen de la bandera roja

Lógica de activación

{
  "any_of": [
    {
      "finding": "hbsag",
      "value": "positive"
    },
    {
      "finding": "anti_hbc_total",
      "value": "positive"
    },
    {
      "finding": "hcv_rna",
      "value": "positive"
    },
    {
      "finding": "hiv_status",
      "value": "positive"
    },
    {
      "finding": "active_uncontrolled_infection",
      "value": true
    }
  ],
  "type": "composite"
}

Notas

Direction "hold" — surfaces a pre-consolidation prerequisite. APL induction (ATRA + ATO ± idarubicin) does not delay for serology; consolidation cycles use anthracycline-containing regimens that warrant HBV-active prophylaxis if serologically at risk. STUB — requires clinical co-lead signoff.

Utilizado por

Algoritmos

• ALGO-APL-1L - ALGO-APL-1L
• ALGO-APL-2L - ALGO-APL-2L

Indicación

• IND-APL-RELAPSED-GEMTUZUMAB - IND-APL-RELAPSED-GEMTUZUMAB
• IND-APL-SALVAGE-ATRA-ATO - IND-APL-SALVAGE-ATRA-ATO