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IDH1 R132 mutation in intrahepatic cholangiocarcinoma after progression on gemcitabine/ci...

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IDRF-CHOLANGIO-IDH1-R132-ACTIONABLE
ArtWarnhinweis
Statusreviewed 2026-05-07 | pending_clinical_signoff
ErkrankungenDIS-CHOLANGIOCARCINOMA
QuellenSRC-ESMO-BTC-2023 SRC-FIGHT-202 SRC-NCCN-HEPATOBILIARY

Ursprung der Roten Flagge

BegriffsbestimmungIDH1 R132 mutation in intrahepatic cholangiocarcinoma after progression on gemcitabine/cisplatin-based therapy. Routes 2L targeted therapy review toward ivosidenib.
Klinische RichtungIntensivierung
Kategoriehigh-risk-biology
Schaltet AlgorithmusALGO-CHOLANGIO-2L

Logik auslösen

{
  "any_of": [
    {
      "finding": "idh1_r132_mutation",
      "value": true
    },
    {
      "finding": "idh1_status",
      "value": "R132"
    },
    {
      "finding": "IDH1",
      "value": "R132C"
    },
    {
      "finding": "BIO-IDH1-MUTATION",
      "value": "R132C"
    }
  ],
  "type": "biomarker"
}

Verwendet von

Algorithmen