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Pituitary adenoma (typically nonfunctioning macroadenoma) causing compressive mass effect...

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IDRF-PITUITARY-MASS-EFFECT-VISUAL-COMPROMISE
TipoSinal de alerta
Estadoreviewed 2026-07-11 | pending_clinical_signoff
DoençasDIS-PITUITARY-ADENOMA
FontesSRC-NCCN-CNS-2025

Origem da bandeira vermelha

DefiniçãoPituitary adenoma (typically nonfunctioning macroadenoma) causing compressive mass effect — visual field deficit / optic chiasm compression, new cranial neuropathy, or hypopituitarism attributable to sellar/suprasellar compression — indicating surgical resection is required rather than observation.
Direcção clínicaintensificar
Categoriadisfunção de órgãos
Algoritmo de deslocamentosALGO-PITUITARY-ADENOMA-1L

Lógica de Desencadeamento

{
  "any_of": [
    {
      "finding": "visual_field_deficit",
      "value": true
    },
    {
      "finding": "optic_chiasm_compression",
      "value": true
    },
    {
      "finding": "pituitary_mass_effect_symptoms",
      "value": true
    },
    {
      "condition": "Macroadenoma with radiographic optic chiasm/nerve compression, new cranial neuropathy, or hypopituitarism attributable to mass effect"
    }
  ],
  "type": "symptom_composite"
}

Notas

STUB pending clinical co-lead signoff (CHARTER §6.1 — dev-mode-exempted). Per the Disease narrative, nonfunctioning pituitary adenoma is managed with surgery only for mass effect / visual compromise; asymptomatic non-compressive NFPA is appropriate for observation with surveillance imaging and is deliberately not modeled as an active-therapy Indication in this KB (mirrors the existing "active surveillance, not a separate indication" pattern used in ALGO-GI-NET-ADVANCED-1L). "visual_field_deficit", "optic_chiasm_compression", and "pituitary_mass_effect_symptoms" are new free-form finding keys — no engine-side data-collection wiring confirmed to exist yet for these keys; the `condition:` free-text leaf in the trigger preserves the clinical criterion regardless of finding wiring status, consistent with existing KB precedent (e.g. RF/algorithm notes in ALGO-RCC-METASTATIC-1L for unwired finding keys).

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