Active or unmanaged infection requiring resolution before initiating cisplatin-based chem...

Visão determinística da entidade fonte YAML. A autoridade clínica permanece com os IDs de fonte citados e estado de assinatura do revisor.

ID	`RF-CERVICAL-INFECTION-SCREENING`
Tipo	Sinal de alerta
Estado	reviewed 2026-04-27 \| pending_clinical_signoff
Doenças	`DIS-CERVICAL`
Fontes	`SRC-ESMO-CERVICAL-2024` `SRC-NCCN-CERVICAL-2025`

Origem da bandeira vermelha

Definição	Active or unmanaged infection requiring resolution before initiating cisplatin-based chemoradiation in cervical cancer: HIV-positive (HPV-driven disease — almost universal HIV testing recommended; CD4 informs cisplatin dosing and pelvic-RT field tolerance), HBV-positive (reactivation risk on prolonged chemoradiation), active pelvic abscess / pyometra (must drain before RT), or active TB.
Direcção clínica	aguentar
Categoria	rastreamento de infecções

Lógica de Desencadeamento

{
  "any_of": [
    {
      "finding": "hiv_status",
      "value": "positive"
    },
    {
      "finding": "hbsag",
      "value": "positive"
    },
    {
      "finding": "active_pelvic_infection",
      "value": true
    },
    {
      "finding": "active_tb",
      "value": true
    }
  ],
  "type": "lab_value"
}

Notas

HIV testing recommended for all cervical cancer patients per NCCN (HPV / HIV co-infection extremely common). HIV+ patients tolerate cisplatin-CRT with ART optimization; CD4 <200 is relative contraindication — coordinate with HIV clinic. HBV+: entecavir/tenofovir prophylaxis during prolonged chemo phases. Pelvic abscess / pyometra: percutaneous drainage / antibiotics first; RT into infected field worsens necrosis. This RF surfaces workup-prerequisites; engine does not switch indication.

Usado por

Indicação

IND-CERVICAL-METASTATIC-1L-PEMBRO-CHEMO-BEV - IND-CERVICAL-METASTATIC-1L-PEMBRO-CHEMO-BEV