Colorectal carcinoma (CRC) · line 1 · None
Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.
Knowledge-base record for audit. Provisional clinical content: this is not a prescription. An oncologist must verify original sources, applicability and review status. Full rules and constraints are in the YAML.
| Line of therapy | 1 |
|---|---|
| Track | standard |
| Linked regimen | None |
| ID | IND-RECTAL-TNT-SHORT-COURSE-RAPIDO |
|---|---|
| Type | Indication |
| Status | reviewed 2026-05-08 | pending_clinical_signoff | actionability review required |
| Diseases | DIS-CRC |
| Sources | SRC-ESMO-CRC-2024 SRC-NCCN-COLON-2025 SRC-RAPIDO-BAHADOER-2021 |
Notes
GI-3 wave C3 chunk (gi3-c3-rectal-tnt-rapido-2026-05-08-2100). Third §17 phased indication after IND-GASTRIC-PERIOP-FLOT4 (GI-2 C1) and IND-ESOPH-RESECTABLE-CROSS-NEOADJUVANT (GI-2 C2). Introduces the `induction` IndicationPhaseStage in clinical content (was schema- available since §17 ratification 2026-05-07; first consumer here). Engine routing from `algo_rectal_*` (D-prefix algorithm extension) to this indication is out of C3 scope — flagged for the D-wave algorithm chunks. The `recommended_regimen` field is left null intentionally because TNT is multi-modality; consumers should iterate `phases:` rather than dereferencing a single regimen ID. D-prefix algorithm flag: rectal-cancer treatment routing (algo_rectal_locally_advanced_*) does not yet exist; this indication is reachable only through direct lookup or via crc.yaml routing once the D-wave landed (separate chunk).
Used By
Algorithms
ALGO-RECTAL-LOCALLY-ADVANCED-TNT- ALGO-RECTAL-LOCALLY-ADVANCED-TNT
Indication
IND-RECTAL-TNT-LONG-COURSE-PRODIGE23- IND-RECTAL-TNT-LONG-COURSE-PRODIGE23