Tumor mutational burden (TMB-high)
Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.
| ID | BIO-TMB-HIGH |
|---|---|
| Type | Biomarker |
| Aliases | TMB-highТумор-мутаційне навантаження |
| Status | pending_clinical_signoff |
| Diseases | None declared |
| Sources | None declared |
Biomarker Facts
| Biomarker type | tmb |
|---|---|
| Measurement | MethodWhole-exome OR comprehensive NGS panel (≥1 Mb) Unitsmutations per megabase |
| Related biomarkers | BIO-MSI-STATUS BIO-DMMR-IHC |
Notes
Foundation One CDx companion diagnostic.
Used By
Biomarker
BIO-LYNCH-PANEL-SPLIT- Lynch syndrome germline panel — gene-resolved (MLH1 / MSH2 / MSH6 / PMS2 / EPCAM)
Diseases
DIS-HNSCC- Head and neck squamous cell carcinoma (HNSCC)
Indications
IND-NSCLC-TMB-HIGH-MET-1L-PEMBRO-MONO- IND-NSCLC-TMB-HIGH-MET-1L-PEMBRO-MONO
Questionnaires
QUEST-NSCLC-1L-STUB- Non-small cell lung cancer — first line