Onco Wiki / drapeau rouge

Exposition professionnelle documentée aux amines aromatiques — benzidine, 2-naphthylamine, 4-aminobiphes...

Vue déterministe de l'entité source de la LJAM. L'autorité clinique demeure avec les ID de la source cités et l'état d'approbation de l ́examinateur.

IDRF-OCC-AROMATIC-AMINES-MALIGNANCY-PREVENTION
TypeSignal d’alerte
Étatreviewed 2026-05-18 | pending_clinical_signoff
MaladiesDIS-UROTHELIAL
SourcesSRC-NCCN-BCELL-2025

Origine du drapeau rouge

DéfinitionDocumented occupational aromatic-amine exposure — benzidine, 2-naphthylamine, 4-aminobiphenyl — primarily in historical pre-regulation dye, rubber, leather, pigment, and chemical-manufacturing industries (mostly pre-1980s in regulated countries; ongoing in unregulated jurisdictions). IARC Group 1 carcinogen for bladder cancer. Engine routes to PreventionPlan recommending annual urinalysis + cytology + low-threshold cystoscopy for hematuria + smoking cessation.
Direction cliniqueenquêter
Catégorieautres

Logique de déclenchement

{
  "any_of": [
    {
      "finding": "occupational_aromatic_amine_exposure_documented",
      "value": true
    },
    {
      "finding": "occupational_dye_rubber_leather_industry_pre_regulation",
      "value": true
    }
  ],
  "type": "lab_value"
}

Notes

Prevention-persona RedFlag for aromatic-amines → urothelial bladder cancer prevention. Fires on documented occupational exposure. DIS-UROTHELIAL anchor preferred but using DIS-HCC as fallback if not in KB on this branch. STUB pending two-Clinical-Co-Lead signoff per CHARTER §6.1 dev-mode.

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Indication