Pheochromocytoma and paraganglioma (PPGL) · line 1 · Preoperative alpha-adrenergic blockade (phenoxybenzamine, before pheochromocytoma/paraganglioma surgery)
Vue déterministe de l'entité source de la LJAM. L'autorité clinique demeure avec les ID de la source cités et l'état d'approbation de l ́examinateur.
Contenu clinique provisoire : il ne s'agit pas d'une ordonnance. Un oncologue doit vérifier les sources originales, l'applicabilité et le statut de révision.
| Ligne thérapeutique | 1 |
|---|---|
| Voie | local_therapy |
| Régime lié | REG-ALPHA-BLOCKADE-PREOP-PHEO |
| ID | IND-PHEO-LOCALIZED-1L-ALPHA-BLOCKADE-ADRENALECTOMY |
|---|---|
| Type | Indication |
| État | examinés 2026-07-11 |
| Maladies | DIS-PHEOCHROMOCYTOMA |
| Sources | SRC-ENDOCRINE-SOCIETY-PPGL-2014 SRC-NCCN-NET-2025 |
Notes
Coverage-enabling local-therapy indication for DIS-PHEOCHROMOCYTOMA. Models surgery NARRATIVELY (via stage_requirements/rationale/do_not_do) rather than via the phases:/surgery_id mechanism used by the meningioma gold-standard example, because no Surgery/Procedure entity for laparoscopic or cortical-sparing adrenalectomy exists in the KB yet and creating one was outside the entity set this pass was scoped to (Algorithm/Indication/Regimen/Drug/RedFlag/Source only) -- flagged as a follow-up PR on the Disease file. recommended_regimen therefore points at the mandatory alpha-blockade regimen (REG-ALPHA-BLOCKADE-PREOP-PHEO), the actual drug-level component of this pathway, with the hard RF-PHEO-INADEQUATE-ALPHA-BLOCKADE gate carrying the sequencing rule. Requires endocrine surgery / anesthesiology co-lead signoff before clinical publication.
Utilisé par
Algorithmes
ALGO-PHEO-1L- ALGO-PHEO-1L
Maladie
DIS-PHEOCHROMOCYTOMA- Phéochromocytome et paragangliome (PPGL)
Signal d’alerte
RF-PHEO-INADEQUATE-ALPHA-BLOCKADE- Pheochromocytoma / paraganglioma surgery (adrenalectomy) is planned or imminent WITHOUT d...
Protocole thérapeutique
REG-ALPHA-BLOCKADE-PREOP-PHEO- blocus alpha-adrénergique préopératoire (phenoxybenzamine, avant le phéochromocytome/paragan...