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Historia de infección por esquistosoma hematobium (óvulos positivos en la orina, serología positiva, o...

Vista determinista de la entidad fuente YAML. La autoridad clínica sigue con los ID de fuente citados y estado de firma del revisor.

IDRF-SCHISTOSOMA-HAEMATOBIUM-BLADDER-PREVENTION
TipoSeñal de alerta
Situaciónreviewed 2026-05-18 | pending_clinical_signoff
EnfermedadesDIS-UROTHELIAL
FuentesSRC-IARC-MONO-100B-2012 SRC-NCCN-BLADDER-2025

Origen de la bandera roja

DefiniciónHistory of Schistosoma haematobium infection (positive ova in urine, positive serology, or documented endemic-region exposure with suggestive urinary tract symptoms) in an individual without a current bladder cancer diagnosis. IARC Group 1 carcinogen (S. haematobium) — established etiological driver of bladder squamous cell carcinoma (SCC), the dominant histology in endemic regions (sub-Saharan Africa, Middle East, parts of South America). Praziquantel cures active infection but does NOT reverse chronic urothelial inflammation / squamous metaplasia from prior burden; surveillance (urinalysis, cytology, cystoscopy for any new hematuria) is the dominant prevention modality. Prevention-persona RedFlag (§20 ratification 2026-05-18).
Dirección clínicainvestigación
Categoríaotros

Lógica de activación

{
  "any_of": [
    {
      "finding": "schistosoma_haematobium_history",
      "value": "positive"
    },
    {
      "finding": "schistosoma_haematobium_ova_urine",
      "value": "positive"
    },
    {
      "finding": "schistosoma_haematobium_serology",
      "value": "positive"
    }
  ],
  "type": "lab_value"
}

Notas

Prevention-persona RedFlag for S. haematobium-driven bladder SCC prevention. Fires on any documented exposure history with confirmatory testing. Engine routes to PreventionPlan recommending praziquantel (if active infection) + lifetime urinary surveillance (urinalysis q6-12mo, cytology + cystoscopy for any new hematuria). STUB pending Co-Lead review. Cancer scope: anchored to DIS-UROTHELIAL. S. haematobium-driven bladder cancers are predominantly SCC histology (distinct from urothelial / transitional cell carcinoma that dominates Western cohorts) — engine surfaces this distinction in the prevention rationale prose. Geographic context: Ukraine is non-endemic; this RF is relevant for patients with diaspora / refugee / travel / origin history from sub-Saharan Africa, Egypt, Sudan, Yemen, parts of South America.

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