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Legacy Burkitt high-risk trigger for algorithm review. A fired flag alone does not establ...

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IDRF-BURKITT-HIGH-RISK
TipoSeñal de alerta
Situaciónpending_clinical_signoff
EnfermedadesDIS-BURKITT
FuentesSRC-ESMO-BURKITT-2024 SRC-NCCN-BCELL-2025

Origen de la bandera roja

DefiniciónLegacy Burkitt high-risk trigger for algorithm review. A fired flag alone does not establish eligibility for the encoded high-risk/no-proven-CNS CODOX/IVAC reference.
Dirección clínicaintensificar
Categoríahigh-risk-biology
Algoritmo de cambiosALGO-BURKITT-1L

Lógica de activación

{
  "any_of": [
    {
      "finding": "burkitt_high_risk",
      "value": true
    },
    {
      "finding": "cns_involvement",
      "value": true
    },
    {
      "finding": "ldh_above_3x_uln",
      "value": true
    },
    {
      "finding": "leukemic_phase",
      "value": true
    },
    {
      "finding": "bulky_abdominal",
      "value": true
    }
  ],
  "type": "composite_clinical"
}

Notas

Trigger logic is retained for legacy trace compatibility, not validated as a complete risk classifier. The indication separately requires explicit high-risk and CNS-negative confirmation; CNS involvement requires a separate protocol. This flag does not mandate CODOX/IVAC or choose an automatic alternative.

Utilizado por

Algoritmos

Indicación