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Legacy Burkitt high-risk trigger for algorithm review. A fired flag alone does not establ...

Deterministische Ansicht der Quelle YAML Entität. Klinische Autorität bleibt mit den zitierten Quell-IDs und Rezensenten Sign-off Zustand.

IDRF-BURKITT-HIGH-RISK
ArtWarnhinweis
Statuspending_clinical_signoff
ErkrankungenDIS-BURKITT
QuellenSRC-ESMO-BURKITT-2024 SRC-NCCN-BCELL-2025

Ursprung der Roten Flagge

BegriffsbestimmungLegacy Burkitt high-risk trigger for algorithm review. A fired flag alone does not establish eligibility for the encoded high-risk/no-proven-CNS CODOX/IVAC reference.
Klinische RichtungIntensivierung
Kategoriehigh-risk-biology
Schaltet AlgorithmusALGO-BURKITT-1L

Logik auslösen

{
  "any_of": [
    {
      "finding": "burkitt_high_risk",
      "value": true
    },
    {
      "finding": "cns_involvement",
      "value": true
    },
    {
      "finding": "ldh_above_3x_uln",
      "value": true
    },
    {
      "finding": "leukemic_phase",
      "value": true
    },
    {
      "finding": "bulky_abdominal",
      "value": true
    }
  ],
  "type": "composite_clinical"
}

Anmerkungen

Trigger logic is retained for legacy trace compatibility, not validated as a complete risk classifier. The indication separately requires explicit high-risk and CNS-negative confirmation; CNS involvement requires a separate protocol. This flag does not mandate CODOX/IVAC or choose an automatic alternative.

Verwendet von

Algorithmen

Anwendungsgebiet