Onco Wiki / Bandeira vermelha

Consumo de álcool pesado — ≥3 bebidas padrão por dia em homens, ≥2 bebidas padrão...

Visão determinística da entidade fonte YAML. A autoridade clínica permanece com os IDs de fonte citados e estado de assinatura do revisor.

IDRF-UNIVERSAL-HEAVY-ALCOHOL-MULTI-CANCER
TipoSinal de alerta
Estadoreviewed 2026-05-18 | pending_clinical_signoff
DoençasNenhuma declaração
FontesSRC-IARC-100E-ALCOHOL SRC-WCRF-AICR-CUP-2018

Origem da bandeira vermelha

DefiniçãoHeavy alcohol use — ≥3 standard drinks per day in men, ≥2 standard drinks per day in women (one US-standard drink = 14 g pure ethanol). IARC Monograph 100E (2012) and the IARC Working Group on Alcoholic Beverages and Ethanol classify alcoholic beverages as Group 1 carcinogen with sufficient evidence for ≥7 cancer types: oral cavity, pharynx, larynx, oesophagus (squamous cell), liver (HCC), colorectum, and female breast. WCRF / AICR Continuous Update Project (2018) adds gastric cardia and probable evidence for pancreas. Dose-response is supra-linear for upper-aerodigestive cancers (multiplicative synergy with tobacco — combined heavy use 10-100× baseline risk for oral / oesophageal cancers) and approximately log-linear for breast (HR ~1.05-1.10 per drink/day). No safe lower threshold for cancer risk has been established (ESC 2018, ICRP 2020). Universal RedFlag (relevant_diseases ["*"]) —...
Direcção clínicainvestigar
CategoriaOutros

Lógica de Desencadeamento

{
  "any_of": [
    {
      "finding": "heavy_alcohol_use_documented",
      "value": true
    }
  ],
  "type": "composite_score"
}

Notas

Pre-triage universal RedFlag — heavy alcohol use (≥3 drinks/d men, ≥2 drinks/d women) per IARC 100E 7-cancer cluster. Authoring intent: cessation counseling (motivational interviewing + AUD-pharmacotherapy per AUDIT-C / DSM-5 severity stratification) + alcohol-related-cancer screening adjustment (HCC US+AFP q6mo if cirrhosis; UADT low-threshold; breast / CRC per age-and-modality standards). With relevant_diseases=["*"], engine does NOT attach Indication tracks via prevention path (plan.py:297 excludes "*") — universal Indications anchored to DIS-HCC are documentation / sidecar candidates pending future engine extension. STUB pending two-Clinical-Co-Lead signoff per CHARTER §6.1 dev-mode.

Usado por

Indicação