Onco Wiki / Regimen

I-131 MIBG radiopharmaceutical therapy (MIBG-avid metastatic pheochromocytoma/paraganglioma)

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

Knowledge-base record for audit. Provisional clinical content: this is not a prescription. An oncologist must verify original sources, applicability and review status. Full rules and constraints are in the YAML.

Source YAML: complete record

ComponentsDRUG-IODINE-131-MIBG
IDREG-IODINE-131-MIBG-PHEO
TypeRegimen
Statusreviewed 2026-07-11 | pending_clinical_signoff
DiseasesNone declared
SourcesSRC-NCCN-NET-2025

Notes

Requires a positive diagnostic MIBG scan (MIBG avidity) before therapeutic administration -- this is a prerequisite modelled as a free-text decision-tree condition in ALGO-PHEO-1L rather than a Test/Biomarker entity (none exists in the KB for MIBG-scan positivity as of this authoring pass). Exact activity/kg dosing intentionally left qualitative pending maintainer verification -- see DRUG-IODINE-131-MIBG. STUB pending clinical co-lead signoff (CHARTER §6.1, dev-mode-exempted).

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Indication