Sofosbuvir/Velpatasvir 12 weeks
Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.
Knowledge-base record for audit. Provisional clinical content: this is not a prescription. An oncologist must verify original sources, applicability and review status. Full rules and constraints are in the YAML.
| Components | DRUG-SOFOSBUVIR-VELPATASVIR |
|---|
| ID | REG-DAA-SOF-VEL |
|---|---|
| Type | Regimen |
| Status | reviewed 2026-04-24 | pending_clinical_signoff |
| Diseases | None declared |
| Sources | SRC-EASL-HCV-2023 SRC-ESMO-MZL-2024 SRC-MOZ-UA-LYMPH-2013 |
Notes
First-line antiviral regimen for HCV-associated lymphoproliferative disease. Achieves SVR12 (cure) in >95% of treatment-naive non- cirrhotic patients. Lymphoma regression often follows viral clearance in 4-12 months; formal reassessment at 6 months.
Used By
Access Pathways
AP-DAA-SOF-VEL-NSZU- Sofosbuvir/velpatasvir DAA via НСЗУ HCV programme (fully reimbursed)
Algorithms
ALGO-NMZL-1L- ALGO-NMZL-1LALGO-SMZL-1L- ALGO-SMZL-1L
Indication
IND-CHRONIC-HCV-HBV-COINFECTION-PREVENTION-COMBINATION-ANTIVIRAL- IND-CHRONIC-HCV-HBV-COINFECTION-PREVENTION-COMBINATION-ANTIVIRALIND-CHRONIC-HCV-PREVENTION-DAA- IND-CHRONIC-HCV-PREVENTION-DAAIND-HCV-MZL-1L-ANTIVIRAL- IND-HCV-MZL-1L-ANTIVIRALIND-HCV-MZL-1L-BR-AGGRESSIVE- IND-HCV-MZL-1L-BR-AGGRESSIVEIND-NMZL-1L-HCV-POSITIVE- IND-NMZL-1L-HCV-POSITIVEIND-SMZL-1L-HCV-POSITIVE- IND-SMZL-1L-HCV-POSITIVE