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Histologic transformation to DLBCL (rapid progression, new constitutional symptoms, LDH s...

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

Red Flag Origin

Trigger Logic

{
  "any_of": [
    {
      "finding": "biopsy_shows_dlbcl",
      "value": true
    },
    {
      "finding": "smzl_transformation_suspected",
      "value": true
    }
  ],
  "type": "composite_clinical"
}

Notes

Transformation to DLBCL changes the disease classification entirely — the engine should hand off to DLBCL Algorithm with the DLBCL biopsy result.

Used By

Algorithms

• ALGO-SMZL-2L - ALGO-SMZL-2L