Metastatic salivary gland carcinoma with ECOG ≥3 OR rapid progression — palliative suppor...

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

ID	`RF-SALIVARY-ADVANCED-PALLIATIVE`
Type	Red flag
Status	reviewed 2026-04-30 \| pending_clinical_signoff
Diseases	`DIS-SALIVARY`
Sources	`SRC-ESMO-SALIVARY` `SRC-NCCN-HEAD-AND-NECK`

Red Flag Origin

Definition	Metastatic salivary gland carcinoma with ECOG ≥3 OR rapid progression — palliative supportive care + symptom-directed RT only.
Clinical direction	de-escalate
Category	frailty-age

Trigger Logic

{
  "all_of": [
    {
      "comparator": "==",
      "finding": "stage",
      "threshold": "metastatic"
    },
    {
      "any_of": [
        {
          "comparator": ">=",
          "finding": "ecog_status",
          "threshold": 3
        },
        {
          "comparator": "==",
          "finding": "rapid_progression",
          "threshold": true
        }
      ]
    }
  ],
  "type": "composite_clinical"
}

Notes

Salivary gland cancer histologically diverse. Metastatic disease has no SoC with proven OS benefit — palliative taxane+platinum most-used. Frailty/ECOG ≥3 → BSC + palliative RT only.

Used By

No reverse references found in the YAML corpus.