Onco Wiki / Red flag

Age ≥80 + ECOG ≥2 — nivo+ipi prohibitive; nivo+rela or pembro mono.

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

Red Flag Origin

Trigger Logic

{
  "all_of": [
    {
      "comparator": ">=",
      "finding": "age_years",
      "threshold": 80
    },
    {
      "comparator": ">=",
      "finding": "ecog_status",
      "threshold": 2
    }
  ],
  "type": "composite_clinical"
}

Notes

RELATIVITY-047 nivo+rela better tolerated.

Used By

Algorithms

• ALGO-MELANOMA-METASTATIC-2L - ALGO-MELANOMA-METASTATIC-2L