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Fit performance status (ECOG 0-1): patient is fully active or restricted in physically st...

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

IDRF-FITNESS-ECOG-FIT
TypeRed flag
Statusreviewed 2026-04-27 | pending_clinical_signoff
DiseasesNone declared
SourcesSRC-ESMO-DLBCL-2024 SRC-NCCN-BCELL-2025

Red Flag Origin

DefinitionFit performance status (ECOG 0-1): patient is fully active or restricted in physically strenuous activity but ambulatory and able to carry out light work. Eligible for full-dose chemotherapy and intensive regimens (CHOEP, BEACOPP-escalated, HD-MTX, ASCT consolidation, CAR-T).
Clinical directionintensify
Categoryfitness-eligibility

Trigger Logic

{
  "any_of": [
    {
      "comparator": "<=",
      "finding": "ecog",
      "threshold": 1
    }
  ],
  "type": "composite_score"
}

Notes

Pan-disease eligibility gate. ECOG 0-1 is the canonical entry criterion for intensified regimens across DLBCL (CHOEP-21 in age ≤60 with elevated LDH per German High-Grade NHL Study Group), Hodgkin (BEACOPP-escalated), Burkitt (CODOX-M/IVAC, DA-EPOCH-R), CAR-T eligibility. Used in conjunction with organ-function gates. Conflict-resolution: when ECOG-FIT fires alongside RF-ORGAN-* de-escalation, organ-dysfunction wins (de-escalation has higher severity). Replaces free-text "ecog 0-1" all_of clauses across algorithms.

Used By

Algorithms