Bowel perforation, severe malabsorption (albumin <2.5 g/dL), or surgical complication — d...

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

ID	`RF-EATL-ORGAN-DYSFUNCTION`
Type	Red flag
Status	reviewed 2026-04-25 \| pending_clinical_signoff
Diseases	`DIS-EATL`
Sources	`SRC-ESMO-PTCL-2024` `SRC-NCCN-BCELL-2025`

Red Flag Origin

Definition	Bowel perforation, severe malabsorption (albumin <2.5 g/dL), or surgical complication — defer CHOEP induction until nutritional/surgical stabilization; parenteral nutrition + delayed-onset chemo schedule.
Clinical direction	hold
Category	organ-dysfunction

Trigger Logic

{
  "any_of": [
    {
      "finding": "bowel_perforation",
      "value": true
    },
    {
      "comparator": "<",
      "finding": "albumin_g_dl",
      "threshold": 2.5
    },
    {
      "finding": "surgical_complication_active",
      "value": true
    }
  ],
  "type": "composite_clinical"
}

Notes

EATL frequently presents with perforation/obstruction requiring emergent surgery. Chemo cannot start safely until ECOG recovers and nutrition stabilizes. Multi-disciplinary surgery-onc-nutrition path.

Used By

No reverse references found in the YAML corpus.