Pheochromocytoma and paraganglioma (PPGL) · None

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

Knowledge-base record for audit. Provisional clinical content: this is not a prescription. An oncologist must verify original sources, applicability and review status. Full rules and constraints are in the YAML.

Source YAML: complete record

Track	aggressive
Linked regimen	`None`

ID	`IND-SDH-CARRIER-INTENSIFIED`
Type	Indication
Status	reviewed 2026-05-18 \| pending_clinical_signoff
Diseases	`DIS-PHEOCHROMOCYTOMA`
Sources	`SRC-NCCN-BCELL-2025`

Notes

STUB — v0.2-B confirmed-carrier intensified track (SDH-deficiency syndromes). Sibling — IND-SDH-CARRIER-SURVEILLANCE. §15.2 C4 ≥2-tracks invariant. Severity CRITICAL inherited from RF given SDHB pediatric-onset aggressive paraganglioma + RCC risk.

Used By

Indication

IND-SDH-CARRIER-SURVEILLANCE - IND-SDH-CARRIER-SURVEILLANCE

Red flag

RF-SDH-CONFIRMED-CARRIER - Confirmed germline pathogenic / likely-pathogenic variant in one of the SDHx genes — SDHB...