Ovarian carcinoma (high-grade serous predominant) · line 2 · Rucaparib maintenance (recurrent platinum-sensitive ovarian, ARIEL3)
Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.
Knowledge-base record for audit. Provisional clinical content: this is not a prescription. An oncologist must verify original sources, applicability and review status. Full rules and constraints are in the YAML.
| Line of therapy | 2 |
|---|---|
| Track | aggressive |
| Linked regimen | REG-RUCAPARIB-MAINT-OVARIAN |
| ID | IND-OVARIAN-MAINT-PARPI-RUCAPARIB |
|---|---|
| Type | Indication |
| Status | reviewed 2026-04-27 | pending_clinical_signoff |
| Diseases | DIS-OVARIAN |
| Sources | SRC-ARIEL3-COLEMAN-2017 SRC-ESMO-OVARIAN-2024 SRC-NCCN-OVARIAN-2025 |
Notes
ESCAT IA. UA-access: rucaparib not registered as of 2026-04 — олапариб (BRCA-mut) і нірапариб (HRD+) є реалістичні UA-доступні альтернативи.
Used By
Algorithms
ALGO-OVARIAN-2L- ALGO-OVARIAN-2L
Indication
IND-OVARIAN-2L-PLAT-SENS-CARBO-GEM-BEV- IND-OVARIAN-2L-PLAT-SENS-CARBO-GEM-BEVIND-OVARIAN-2L-PLAT-SENS-CARBO-PLD-BEV- IND-OVARIAN-2L-PLAT-SENS-CARBO-PLD-BEV