Onco Wiki / Indication

Non-small cell lung cancer · line 1 · Ensartinib monotherapy (eXalt3) — ALK+ NSCLC, 1L metastatic

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

Knowledge-base record for audit. Provisional clinical content: this is not a prescription. An oncologist must verify original sources, applicability and review status. Full rules and constraints are in the YAML.

Source YAML: complete record

Line of therapy1
Trackaggressive
Linked regimenREG-ENSARTINIB-ALK-1L-NSCLC
IDIND-NSCLC-ALK-1L-ENSARTINIB
TypeIndication
Statusreviewed 2026-04-29 | pending_clinical_signoff
DiseasesDIS-NSCLC
SourcesSRC-ESMO-NSCLC-METASTATIC-2024 SRC-NCCN-NSCLC-2025

Notes

STUB — pending Clinical Co-Lead sign-off. Aggressive-track 1L alternative to alectinib for ALK+ metastatic NSCLC (eXalt3 registration). Existing IND-NSCLC-ALK-MET-1L (alectinib, Cat 1) remains standard-track default. eXalt3 source stub not yet in KB — citation flagged in commit body for source-ingest follow-up.

Used By

No reverse references found in the YAML corpus.