Onco Wiki / Indication

Multiple Myeloma · line 3 · Teclistamab BCMA × CD3 bispecific (with step-up dosing) — continuous SC weekly

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

Knowledge-base record for audit. Provisional clinical content: this is not a prescription. An oncologist must verify original sources, applicability and review status. Full rules and constraints are in the YAML.

Source YAML: complete record

Line of therapy3
Trackaggressive
Linked regimenREG-TECLISTAMAB
IDIND-MM-RR-3L-TECLISTAMAB
TypeIndication
Statusreviewed 2026-04-29 | pending_clinical_signoff
DiseasesDIS-MM
SourcesSRC-ESMO-MM-2023 SRC-MAJESTEC-1-MOREAU-2022 SRC-NCCN-MM-2025

Notes

STUB — requires two clinical co-lead signoffs before publication (CHARTER §6.1). Sibling to existing IND-MM-4L-TECLISTAMAB (4L framing); this entity uses RR-3L framing per Tier-2 manifest (tier2-ind-mm-2026-05-01-021). MajesTEC-1 source available; NCCN-MM-2025 + ESMO-MM-2023 supplementary citations satisfy Q4 ≥2-source axis.

Used By

No reverse references found in the YAML corpus.