Onco Wiki / Indication

Gastric / GEJ adenocarcinoma · line 1 · FLOT

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

Knowledge-base record for audit. Provisional clinical content: this is not a prescription. An oncologist must verify original sources, applicability and review status. Full rules and constraints are in the YAML.

Source YAML: complete record

Line of therapy1
Trackaggressive
Linked regimenREG-FLOT
IDIND-GASTRIC-OLIGOMET-SYSTEMIC-PLUS-LOCAL
TypeIndication
Statusreviewed 2026-05-08 | pending_clinical_signoff | actionability review required
DiseasesDIS-GASTRIC
SourcesSRC-ESMO-GASTRIC-2024 SRC-NCCN-GASTRIC-2025 SRC-OMEC-1-KROESE-2023 SRC-RENAISSANCE-AIO-FLOT5

Notes

Gastric oligometastatic systemic-plus-local track per OMEC-1 consensus + RENAISSANCE / AIO-FLOT5 design. Confidence: moderate (consensus + ongoing-trial design; NCCN 2B). RENAISSANCE primary OS publication pending — re-grade to 2A and evidence_level high once full results published (D2 follow-up). §17 phases: NOT populated for v0.1 (planning doc gi2_wave §4.5 recommendation 2). Local-therapy entities (metastasectomy Surgery, SBRT RadiationCourse) for gastric oligomet are future Phase C extensions. Sequence (induction FLOT → restaging → local therapy → adjuvant FLOT) described in description / rationale / do_not_do text only. recommended_regimen: REG-FLOT (backfilled 2026-05-08 after C1 PR #435 created REG-FLOT; closes #438). Algorithm wiring deferred — ALGO-GASTRIC-METASTATIC-1L does not yet have an oligomet branch. D2 follow-up: extend algorithm with oligomet decision step gated by RF-OLIGOMET-DEFINITION. Engine smoke (synthetic patient: gastric, mets=liver_2_lesions + 1_lymph_node, ECOG 1, primary_controllable=true, HER2 negative): RF-OLIGOMET-DEFINITION fires; no algorithm branch consumes it yet. Indication is reachable via direct ID lookup but not via current decision-tree rou...

Used By

Algorithms

Indication

Red flag