Onco Wiki / Disease

Mycosis Fungoides / Sézary Syndrome

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

IDDIS-MF-SEZARY
TypeDisease
Aliases
MFMF/SSSézaryГрибоподібний мікоз / Синдром Сезарі
Statusreviewed 2026-04-25 | pending_clinical_signoff
DiseasesNone declared
SourcesSRC-NCCN-BCELL-2025

Informational support. All recommendations must be verified by a qualified oncologist. Engineering checks are not clinical validation or treatment approval.

Source YAML

icd_o_3_morphology9700/3
icd_10C84.0
who_classificationMature T-cell neoplasms — Mycosis fungoides / Sézary syndrome per WHO 5th ed.

Capabilities

Notes

TNMB staging unique to MF (skin Tumor + Node + Metastasis + Blood involvement). Treatment fundamentally stage-based: skin-directed (topical steroids, NBUVB, PUVA, TSEBT) for early; systemic (mogamulizumab, brentuximab if CD30+, ECP, methotrexate, romidepsin, alemtuzumab) for advanced. Sézary syndrome variant always advanced. Out of Tier 1 detailed treatment scope for now — placeholder disease entity with skin-directed-then-systemic algorithm planned for next iteration.

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