Progesterone receptor (PR)
Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.
| ID | BIO-PROGESTERONE-RECEPTOR |
|---|---|
| Type | Biomarker |
| Aliases | Progesterone receptorПрогестероновий рецептор (ПР) |
| Status | pending_clinical_signoff |
| Diseases | None declared |
| Sources | None declared |
Biomarker Facts
| Biomarker type | protein_expression_ihc |
|---|---|
| Measurement | MethodImmunohistochemistry on FFPE tumor tissue (ASCO/CAP-validated antibody) Unitspercent of tumor nuclei staining Typical range
|
| Related biomarkers | BIO-ESTROGEN-RECEPTOR |
Notes
Companion biomarker to ER. Together define HR-positive subtype. Discordance ER+/PR- (~10-15%) more aggressive than ER+/PR+ but still endocrine-therapy-eligible.
Used By
Biomarker
BIO-ESTROGEN-RECEPTOR- Estrogen receptor (ER)
Indications
IND-BREAST-HR-POS-MET-1L-CDKI- IND-BREAST-HR-POS-MET-1L-CDKI
Questionnaires
QUEST-BREAST-1L-STUB- Invasive breast cancer — first line
Red flag
RF-BREAST-TNBC- Triple-negative breast cancer (TNBC): estrogen receptor (ER) <1% nuclear staining on IHC...
Tests
TEST-ER-PR-IHC- ER + PR immunohistochemistry on tumor